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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRC1 All Species: 10.61
Human Site: T491 Identified Species: 23.33
UniProt: O43663 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43663 NP_003972.1 620 71607 T491 K A R K L N T T T M S N A T A
Chimpanzee Pan troglodytes XP_510600 770 87232 L641 T P S K R R G L V P N T P G K
Rhesus Macaque Macaca mulatta XP_001098763 640 74381 T491 K A R K L N T T T M S N A T A
Dog Lupus familis XP_849989 620 71878 T491 K V R K L N T T T M S N A T A
Cat Felis silvestris
Mouse Mus musculus Q99K43 603 70244 R474 T P R T P S K R P G Q T P K K
Rat Rattus norvegicus NP_001100999 606 70580 Q477 T P S K R P G Q T P N K C G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001073221 262 30135 L134 D K N L C D I L C V S N F S I
Frog Xenopus laevis NP_001080868 609 71186 P478 N K R R M I A P S T P S K C R
Zebra Danio Brachydanio rerio NP_956528 605 70353 F476 R T P T K R R F L G S T T P C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572659 607 71048 S479 S N R G I H G S T S S L K K T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785901 748 86941 E614 A R K R I T E E E M L H G S K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.3 89.8 93 N.A. 81.2 81.2 N.A. N.A. 28.5 61.9 59 N.A. 22.2 N.A. N.A. 31.2
Protein Similarity: 100 78.4 92.5 95.8 N.A. 88.3 88.8 N.A. N.A. 35.6 76.2 73.3 N.A. 43.5 N.A. N.A. 48.1
P-Site Identity: 100 6.6 100 93.3 N.A. 6.6 13.3 N.A. N.A. 13.3 6.6 6.6 N.A. 20 N.A. N.A. 6.6
P-Site Similarity: 100 13.3 100 93.3 N.A. 13.3 20 N.A. N.A. 33.3 33.3 13.3 N.A. 40 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 19 0 0 0 0 10 0 0 0 0 0 28 0 28 % A
% Cys: 0 0 0 0 10 0 0 0 10 0 0 0 10 10 10 % C
% Asp: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 10 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 10 0 0 28 0 0 19 0 0 10 19 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 19 10 10 0 0 0 0 0 0 0 10 % I
% Lys: 28 19 10 46 10 0 10 0 0 0 0 10 19 19 37 % K
% Leu: 0 0 0 10 28 0 0 19 10 0 10 10 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 37 0 0 0 0 0 % M
% Asn: 10 10 10 0 0 28 0 0 0 0 19 37 0 0 0 % N
% Pro: 0 28 10 0 10 10 0 10 10 19 10 0 19 10 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % Q
% Arg: 10 10 55 19 19 19 10 10 0 0 0 0 0 0 10 % R
% Ser: 10 0 19 0 0 10 0 10 10 10 55 10 0 19 0 % S
% Thr: 28 10 0 19 0 10 28 28 46 10 0 28 10 28 10 % T
% Val: 0 10 0 0 0 0 0 0 10 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _